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Symbol
Name
ID
Tapbp
TAP binding protein
MGI:1201689
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Chronic sinusitis
Chronic otitis media
Bronchiolitis
Recurrent bronchitis
Disease(s) Associated with TAPBP
MHC class I deficiency

Mouse Phenotypes
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
abnormal lymphocyte physiology
abnormal NK cell physiology
abnormal cytotoxic T cell physiology
decreased cytotoxic T cell cytolysis
abnormal dendritic cell antigen presentation
abnormal antigen presentation via MHC class I
decreased level of surface class I molecules
defective assembly of class I molecules
Availability Mouse Genotype
Tapbptm1Gjh/Tapbptm1Gjh
Tapbptm1Luc/Tapbptm1Luc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory